Article

An active Unc13A is Reboundless in sleep homeostasis

2025-06-29

Abstract excerpt

One of the major characteristics of sleep is homeostatic sleep rebound following sleep loss. While the molecular mechanisms of baseline sleep regulation have been intensively studied, a specific molecular understanding of sleep rebound remains elusive. Here, we show that a constitutively active form of the Munc13-family presynaptic release factor Unc13A, which lacks the inhibitory Ca 2+ /calmodulin interaction do...

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Literature Corpus work: 88c91c0b-edf6-56bb-b874-aa1e5afce0dd
DOI: 10.1101/2025.06.26.661764

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