Article
The NALCN channel complex is necessary for stabilizing sleep in Caenorhabditis elegans.
G3 (Bethesda, Md.) - 6 Jul 2026
Kamijo Takahiro, Miyazaki Shinichi, Hayashi Yu
Abstract excerpt
Sleep is a fundamental physiological state that is widely conserved across diverse animal species. Caenorhabditis elegans exhibits developmentally timed sleep (DTS) and stress-induced sleep (SIS), which meet the behavioral definition of sleep and are regulated by molecular mechanisms shared with other animals. Here, we studied the sleep-regulating functions of UNC-80, which forms a complex with NCA-1 and NCA-2...
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