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Article

Neuronal machinery of sleep homeostasis in Drosophila.

Neuron - 19 Feb 2014

Donlea Jeffrey M, Pimentel Diogo, Miesenböck Gero

Abstract excerpt

Sleep is under homeostatic control, but the mechanisms that sense sleep need and correct sleep deficits remain unknown. Here, we report that sleep-promoting neurons with projections to the dorsal fan-shaped body (FB) form the output arm of Drosophila's sleep homeostat. Homeostatic sleep control requires the Rho-GTPase-activating protein encoded by the crossveinless-c (cv-c) gene in order to transduce sleep...

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Identifiers

PMID: 24559676
DOI: 10.1016/j.neuron.2013.12.013
PMCID: PMC3969244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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