Article

MondoA Drives Malignancy in cALL through Enhanced Adaptation to Metabolic Stress

2020-11-01

Abstract excerpt

Cancer cells are in most instances characterized by rapid proliferation and uncontrolled cell division. Hence, they must adapt to proliferation-induced metabolic stress through intrinsic or acquired anti-metabolic stress responses to maintain homeostasis and survival. One mechanism to achieve this is to reprogram gene expression in a metabolism-dependent manner. MondoA (also known as MLXIP), a member of the MYC in...

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Literature Corpus work: 88afc41d-938f-5200-a229-dbef08221d8a
DOI: 10.1101/2020.11.01.363986

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