Article
From the (Epi)Genome to Metabolism and Vice Versa; Examples from Hematologic Malignancy.
International journal of molecular sciences - 12 Jun 2021
Karagianni Panagiota, Giannouli Stavroula, Voulgarelis Michael
Abstract excerpt
Hematologic malignancies comprise a heterogeneous group of neoplasms arising from hematopoietic cells or their precursors and most commonly presenting as leukemias, lymphomas, and myelomas. Genetic analyses have uncovered recurrent mutations which initiate or accumulate in the course of malignant transformation, as they provide selective growth advantage to the cell. These include mutations in genes encoding...
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