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Article

Multiomics Analysis of Transcriptome, Epigenome, and Genome Uncovers Putative Mechanisms for Dilated Cardiomyopathy.

BioMed research international - 1 Jan 2021

Liu Li, Huang Jianjun, Liu Yan, Pan Xingshou, Li Zhile, Zhou Liufang, Lai Tengfang, Chen Chengcai, Wei Baomin, Mo Jianjiao, Wei Qinjiang, Yan Wei, Huang Xiannan, Zhang Zhen, Zhang Zhuohua, Huang Meidan, He Fengzhen, Huang Zhaohe

Abstract excerpt

OBJECTIVE: Multiple genes have been identified to cause dilated cardiomyopathy (DCM). Nevertheless, there is still a lack of comprehensive elucidation of the molecular characteristics for DCM. Herein, we aimed to uncover putative molecular features for DCM by multiomics analysis. METHODS: Differentially expressed genes (DEGs) were obtained from different RNA sequencing (RNA-seq) datasets of left ventricle samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33860048
DOI: 10.1155/2021/6653802
PMCID: PMC8024089

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