Article

Astrocytic VMAT2 in the developing prefrontal cortex is required for normal grooming behavior in mice

2021-01-27

Abstract excerpt

Astrocytes control synaptic activity by modulating peri-synaptic concentrations of ion and neurotransmitters including dopamine and, as such, can be critically involved in the modulation of some aspect of mammalian behavior. Here we report that genetic mouse model with a reduced medial prefrontal cortex (mPFC) dopamine levels, arising from astrocyte-specific conditional deletion of vesicular monoamine transporter...

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Literature Corpus work: 888806f9-6da4-5c1b-8fc0-37159483d544
DOI: 10.1101/2021.01.27.428434

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