Article

Gene expression profiling of dendritic cell tolerance dysfunction in women with Systemic lupus erythematosus

2025-12-23

Abstract excerpt

<h4>ABSTRACT</h4> Dendritic cells (DCs) are central regulators of immune tolerance, and disturbances in their phenotype and function contribute to the breakdown of self-tolerance in systemic lupus erythematosus (SLE). Tolerogenic DCs (tolDCs), which suppress autoreactive responses and promote peripheral tolerance, are a promising therapeutic focus in autoimmune diseases. Here, we analyzed the transcriptional prof...

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Literature Corpus work: 8840b405-957f-53db-ba86-6d1ada9a3157
DOI: 10.64898/2025.12.21.695630

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