Article

Nuciferine promotes longevity and fitness in Caenorhabditis elegans through the regulation of the insulin/IGF-1 signaling pathway

2024-01-04

Abstract excerpt

<title>Abstract</title> <p>Nuciferine, as one of the most abundant plant-derived alkaloids, has multiple bioactivities including anti-inflammatory, anti-tumor, and lipid lowering effect. Nevertheless, the anti-aging effects and related mechanisms of nuciferine are rarely reported. In this study, we found that nuciferine significantly prolonged the mean lifespan of <italic>Caenorhabditis elegans</italic> (<italic>...

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Literature Corpus work: 883ff715-20ce-5d4f-8752-03d6c9058ec7
DOI: 10.21203/rs.3.rs-3803683/v1

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