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Gengnianchun Extends the Lifespan of Caenorhabditis elegans via the Insulin/IGF-1 Signalling Pathway.

Oxidative medicine and cellular longevity - 1 Jan 2018

Meng Fanhui, Li Jun, Rao Yanqiu, Wang Wenjun, Fu Yan

Abstract excerpt

Gengnianchun (GNC), a traditional Chinese medicine (TCM), is believed to have beneficial effects on ageing-related diseases, such as antioxidant properties and effects against Aβ-induced toxicity. We previously found that GNC extended the lifespan of Caenorhabditis elegans. However, the mechanism underlying this effect was unclear. In this study, we further explored the mechanisms of GNC using a C. elegans model....

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Identifiers

PMID: 29670680
DOI: 10.1155/2018/4740739
PMCID: PMC5835280

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