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Vitexin and Isovitexin Act through Inhibition of Insulin Receptor to Promote Longevity and Fitness in Caenorhabditis elegans

12 Apr 2022

Abstract excerpt

SCOPE: Vitexin and isovitexin are natural plant nutraceuticals for human health and longevity. This research investigates the underlying mechanisms of vitexin and isovitexin on aging and health. The vital role of DAF-2/insulin-like growth factor-1 receptor (IGFR) is illustrated in the insulin/insulin-like growth signaling pathway (IIS) modulated by vitexin and isovitexin. METHODS AND RESULTS: In vitro, in vivo...

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Share to Genetics, Aging, and Longevity in Model Organisms
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Identifiers

PMID: 35413150
DOI: 10.1002/mnfr.202100845

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