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Trigonelline Extends the Lifespan of C. Elegans and Delays the Progression of Age‐Related Diseases by Activating AMPK, DAF‐16, and HSF‐1

1 Jan 2021

Abstract excerpt

Trigonelline is the main alkaloid with bioactivity presented in fenugreek, which was used in traditional medicine in Asian countries for centuries. It is reported that trigonelline has anti‐inflammatory, anti‐oxidant, and anti‐pathogenic effects. We are wondering whether trigonelline have anti‐aging effect. We found that 50 μM of trigonelline had the best anti‐aging activity and could prolong the lifespan of...

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Identifiers

PMID: 34616504
DOI: 10.1155/2021/7656834

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