Article

IGF2 prevents dopaminergic neuronal loss and decreases intracellular alpha-synuclein accumulation in Parkinson’s disease models

2023-07-03

Abstract excerpt

<title>Abstract</title> <p>Parkinson's disease (PD) is the second most common late-onset neurodegenerative disease and the predominant cause of movement problems. PD is characterized by motor control impairment by extensive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). This selective dopaminergic neuronal loss is in part triggered by intracellular protein inclusions called Lewy bodies...

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Literature Corpus work: 88358ddb-2497-5de1-8fbd-d2a29b7a7560
DOI: 10.21203/rs.3.rs-3039640/v1

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