Article

GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation

2021-12-21

Abstract excerpt

Identifying novel pathways regulating the adaptive immune response in chronic inflammatory diseases such as atherosclerosis is of particular interest in view of developing new therapeutic drugs. Here we report that the lipid receptor GPR55 is highly expressed by splenic B cells and inversely correlates with atheroma plaque size in mice. In human carotid endarterectomy specimen, GPR55 transcript levels were signifi...

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Literature Corpus work: 87f41bcd-cf25-5b23-aa3e-09affdc8aa8f
DOI: 10.1101/2021.12.20.473518

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