Article

<i>Drosophila</i> Filamin exhibits a mechano-protective role during nephrocyte injury via induction of hypertrophic growth

2021-08-20

Abstract excerpt

Podocytes are highly specialized epithelial cells of the kidney glomerulus and are an essential part of the filtration barrier. Due to their position and function in the kidney, they are exposed to constant biomechanical forces such as shear stress and hydrostatic pressure. These forces increase during disease, resulting in podocyte injury and loss. The mechanism by which biomechanical forces are sensed and transd...

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Literature Corpus work: 87aba6d8-a3eb-5035-b28a-57c7a28f58ab
DOI: 10.1101/2021.08.20.457058

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