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Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond

5 Jun 2018

Abstract excerpt

Podocytes are a major component of the glomerular blood filtration barrier, and alterations to the morphology of their unique actin-based foot processes are a common feature of kidney disease. Adjacent foot processes are connected by a specialized intercellular junction known as the slit diaphragm (SD), which serves as the ultimate barrier to regulate passage of macromolecules from the blood. While the link...

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Share to Chronic Kidney Disease and Diabetes
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Identifiers

PMID: 29922234
DOI: 10.3389/fendo.2018.00302

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