Article

Overcoming N-glycosylation challenges through multiplex CRISPR/Cas9-mediated editing of seven glycosyltransferase homologs in Nicotiana benthamiana

2024-06-21

Abstract excerpt

<title>Abstract</title> Utilizing plants for the manufacturing of therapeutic drugs for human and animal disease treatment faces technical and regulatory challenges because of disparities in the N-glycosylation pathway between animals and plants. The key challenge involves differences in the post-translational modification machinery in the N-glycosylation pathway. We used multiplex CRISPR/Cas9 genome editing t...

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Literature Corpus work: 879cfbd8-a91d-5291-afd9-2af4a1838152
DOI: 10.21203/rs.3.rs-4518673/v1

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Overcoming N-glycosylation challenges through multiplex CRISPR/Cas9-mediated editing of seven glycosyltransferase homologs in Nicotiana benthamianaDOI 10.21203/rs.3.rs-4518673/v1Read

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