Article
Characterization of plants expressing the human β1,4-galactosyltrasferase gene.
Plant physiology and biochemistry : PPB - 1 Jul 2015
Schneider Jeannine, Castilho Alexandra, Pabst Martin, Altmann Friedrich, Gruber Clemens, Strasser Richard, Gattinger Pia, Seifert Georg J, Steinkellner Herta
Abstract excerpt
Modification of the plant N-glycosylation pathway towards human type structures is an important strategy to implement plants as expression systems for therapeutic proteins. Nevertheless, relatively little is known about the overall impact of non-plant glycosylation enzymes in stable transformed plants. Here, we analyzed transgenic lines (Nicotiana benthamiana and Arabidopsis thaliana) that stably express a...
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