Article
Transient Recombinant Protein Production in Glycoengineered Nicotiana benthamiana Cell Suspension Culture.
International journal of molecular sciences - 16 Apr 2018
Sukenik Sara C, Karuppanan Kalimuthu, Li Qiongyu, Lebrilla Carlito B, Nandi Somen, McDonald Karen A
Abstract excerpt
Transient recombinant protein production is a promising alternative to stable transgenic systems, particularly for emergency situations in which rapid production of novel therapeutics is needed. In plants, Agrobacterium tumefaciens can be used as a gene delivery vector for transient expression. A potential barrier for plant-based production of human therapeutics is that different glycosylation patterns are found...
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