Article

Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae

2019-09-08

Abstract excerpt

In the last decades in vitro studies highlighted the potential for crosstalk between Hypoxia-Inducible Factor-(HIF) and glucocorticoid-(GC) signalling pathways. However, how this interplay precisely occurs in vivo is still debated. Here, we use zebrafish larvae ( Danio rerio ) to elucidate how and to what degree hypoxic signalling affects the endogenous glucocorticoid pathway and vice versa, in vivo . Firstly,...

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Literature Corpus work: 879041b1-1045-5da2-8c0c-071f6402c589
DOI: 10.1101/748566

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