Article

Lifelong molecular consequences of high Glucocorticoids exposure during development

2023-02-14

Abstract excerpt

Early life stress (ELS) is one of the strongest risk factors for developing psychiatric disorders in humans. As conserved key stress hormones of vertebrates, glucocorticoids (GCs) are thought to play an important role in mediating the effects of ELS exposure in shaping adult phenotypes. In this process, early exposure to high level of GCs may induce molecular changes that alter developmental trajectory of an anima...

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Literature Corpus work: 858b275f-1209-5d28-837c-fb7ea6ecdf79
DOI: 10.1101/2023.02.13.528363

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