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Glucocorticoid-Mediated Developmental Programming of Vertebrate Stress Responsivity

21 Dec 2021

Abstract excerpt

Glucocorticoids, vertebrate steroid hormones produced by cells of the adrenal cortex or interrenal tissue, function dynamically to maintain homeostasis under constantly changing and occasionally stressful environmental conditions. They do so by binding and thereby activating nuclear receptor transcription factors, the Glucocorticoid and Mineralocorticoid Receptors (MR and GR, respectively). The GR, by virtue of...

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PMID: 34992551
DOI: 10.3389/fphys.2021.812195

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