Article

Quantifying posterior effect size distribution of susceptibility loci by common summary statistics

2019-07-25

Abstract excerpt

Testing millions of SNPs in genetic association studies has become standard routine for disease gene discovery, followed by prioritization of the strongest signals based on the set of the smallest P-values. In light of recent re-evaluation of statistical practice, it has been suggested that P-values are unfit as summaries of statistical evidence. Despite this criticism, P-values are commonly used and are unlikely...

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Literature Corpus work: 87698ef6-0425-5153-a599-b86ed65a2792
DOI: 10.1101/714287

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