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Article

Novel bayes factors that capture expert uncertainty in prior density specification in genetic association studies.

Genetic epidemiology - 1 May 2015

Spencer Amy V, Cox Angela, Lin Wei-Yu, Easton Douglas F, Michailidou Kyriaki, Walters Kevin

Abstract excerpt

Bayes factors (BFs) are becoming increasingly important tools in genetic association studies, partly because they provide a natural framework for including prior information. The Wakefield BF (WBF) approximation is easy to calculate and assumes a normal prior on the log odds ratio (logOR) with a mean of zero. However, the prior variance (W) must be specified. Because of the potentially high sensitivity of the WBF...

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PMID: 25727067
DOI: 10.1002/gepi.21891
PMCID: PMC4406822

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CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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