Article
Investigating the influence of aluminium adjuvant on antigen presentation in vitro and T cell responses in vivo
2012-01-01
Abstract excerpt
Aluminium adjuvants (Alum) are the only widely approved adjuvants used in human vaccines, although their mechanism of action remains controversial. It is generally accepted that adjuvants mediate their effects on the adaptive immune system cells via innate antigen presenting cells (APCs), in particular dendritic cells (DCs). In this study the way in which Alum modulates several steps in DC functions that lead to T...
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Identifiers and source
- Literature Corpus work
- 874e6980-9b38-529f-af07-8084aec9a7f8
- DOI
- 10.48730/aepw-hd28