Article
AlOH3-adjuvanted vaccine-induced macrophagic myofasciitis in rats is influenced by the genetic background.
Neuromuscular disorders : NMD - 1 May 2006
Authier François-Jérôme, Sauvat Stéphane, Christov Christo, Chariot Patrick, Raisbeck Grant, Poron Marie-Françoise, Yiou Françoise, Gherardi Romain
Abstract excerpt
Macrophagic myofasciitis (MMF) is a specific histopathologic lesion involved in the persistence for years of aluminum hydroxide [Al(OH)(3)] at the site of previous intramuscular (i.m.) injection. In order to study mechanisms involved persistence of MMF lesions, we set up an experimental model of MMF-lesion in Sprague-Dawley and Lewis rat, by i.m. injections of 10 microL of an Al(OH)(3)-adjuvanted vaccine. An...
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