Article
Comparison of adjuvant and adjuvant-free murine experimental asthma models.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Aug 2009
Conrad M L, Yildirim A O, Sonar S S, Kiliç A, Sudowe S, Lunow M, Teich R, Renz H, Garn H
Abstract excerpt
INTRODUCTION: The most widely used protocol for the induction of experimental allergic airway inflammation in mice involves sensitization by intraperitoneal (i.p.) injections of the antigen ovalbumin (OVA) used in conjunction with the adjuvant aluminium hydroxide (alum). Although adjuvants are frequently used, there are questions regarding the necessity of alum for murine asthma studies due to the...
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