Article
Aluminum adjuvants of vaccines injected into the muscle: Normal fate, pathology and associated disease.
Morphologie : bulletin de l'Association des anatomistes - 1 Jun 2016
Gherardi R K, Aouizerate J, Cadusseau J, Yara S, Authier F J
Abstract excerpt
Aluminum oxyhydroxide (Alhydrogel(®)) is a nano-crystalline compound forming aggregates that has been introduced in vaccine for its immunologic adjuvant effect in 1926. It is the most commonly used adjuvant in human and veterinary vaccines but mechanisms by which it stimulates immune responses remain ill-defined. Although generally well tolerated on the short term, it has been suspected to occasionally cause...
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