Article

Integration of RNA-seq and Ribosome Profiling to Characterize Transcriptional and Translational Estrogen Responses of Genes in Human Breast Cancer

2020-09-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Estrogen is a hormone that is frequently essential in breast cancer to drive key transcriptional programs by interacting with the estrogen receptor alpha that upregulates proliferative and oncogenic genes and represses apoptotic and tumor suppressor genes. Protein-coding targets of estrogen regulation in breast cancer are well-defined. However, long non-coding RNA...

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Literature Corpus work: 871d211c-6003-5bc3-8ac9-a7f9d198189b
DOI: 10.21203/rs.3.rs-74119/v1

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