Article
Gene expression signature of estrogen receptor alpha status in breast cancer.
BMC genomics - 11 Mar 2005
Abba Martín C, Hu Yuhui, Sun Hongxia, Drake Jeffrey A, Gaddis Sally, Baggerly Keith, Sahin Aysegul, Aldaz C Marcelo
Abstract excerpt
BACKGROUND: Estrogens are known to regulate the proliferation of breast cancer cells and to modify their phenotypic properties. Identification of estrogen-regulated genes in human breast tumors is an essential step toward understanding the molecular mechanisms of estrogen action in cancer. To this end we generated and compared the Serial Analysis of Gene Expression (SAGE) profiles of 26 human breast carcinomas...
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