Article

NF1 Loss Remodels Tumor Niches for Immune Evasion

2026-01-12

Abstract excerpt

<h4>Summary</h4> Genetic and transcriptional alterations in cancer cells shape their interactions with immune and stromal compartments, influencing tumor progression, immune evasion, and response to immune checkpoint inhibitors (ICI). Yet, how these interactions are organized within tumor architecture and linked to clinical outcomes remains unclear. Neurofibromin 1 ( NF1 ) is a tumor suppressor gene that is freq...

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Literature Corpus work: 6c3bc7b9-2501-5308-a698-15cc8e86d6c8
DOI: 10.64898/2026.01.11.698818

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