Article
YY1 and a unique DNA repeat element regulates the transcription of mouse CS1 (CD319, SLAMF7) gene.
Molecular immunology - 1 Jul 2013
Dongre Prachi, Mathew Stephen, Akopova Irina, Gryczynski Ignacy, Mathew Porunelloor
Abstract excerpt
CS1 (CD319, CRACC, SLAMF7, novel Ly9) activates NK cell-mediated cytotoxicity and proliferation of B lymphocytes during immune responses. The expression of CS1 is up regulated on B cells in multiple myeloma and systemic lupus erythematosus. In this study we describe the transcriptional regulation...
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