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Article

YY1 and a unique DNA repeat element regulates the transcription of mouse CS1 (CD319, SLAMF7) gene.

Molecular immunology - 1 Jul 2013

Dongre Prachi, Mathew Stephen, Akopova Irina, Gryczynski Ignacy, Mathew Porunelloor

Abstract excerpt

CS1 (CD319, CRACC, SLAMF7, novel Ly9) activates NK cell-mediated cytotoxicity and proliferation of B lymphocytes during immune responses. The expression of CS1 is up regulated on B cells in multiple myeloma and systemic lupus erythematosus. In this study we describe the transcriptional regulation of mouse CS1 (mCS1) gene. We show that mCS1 gene transcription is regulated by YY1 (Ying Yang 1) and a unique (AG)n=36...

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Source

Identifiers

PMID: 23318224
DOI: 10.1016/j.molimm.2012.12.017

Genes

SLAMF7
AFM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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