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Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing <em>Enterobacteriaceae</em>: Insights from Comparative Genomics

2025-06-01

Abstract excerpt

<h4>Background: </h4> /Objectives: Cefiderocol is a novel siderophore cephalosporin with potent in vitro activity against a broad spectrum of Gram-negative bacteria, including carbapenemase-producing Enterobacteriaceae CPE). However, the recent emergence of re-sistance in clinical settings raises important concerns regarding its long-term effective-ness. This study aims to investigate the genomic determinants asso...

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Literature Corpus work
86639b25-5a7b-5218-8795-7c191dfdb42a
DOI
10.20944/preprints202505.2477.v1
Open publication

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Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing <em>Enterobacteriaceae</em>: Insights from Comparative GenomicsDOI 10.20944/preprints202505.2477.v1
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