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High prevalence of cefiderocol resistance in carbapenem-resistant Escherichia coli: A warning from multicenter clinical data in China

6 Aug 2025

Abstract excerpt

Aims This study aimed to evaluate the in vitro efficacy of cefiderocol and other agents against carbapenem-resistant Escherichia coli (CREC) clinical isolates in China and to elucidate the genetic mechanisms underlying cefiderocol resistance. Methods A total of 638 non-duplicated CREC isolates were collected from 27 tertiary hospitals across China. Minimum inhibitory concentrations (MICs) of antimicrobial agents...

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PMID: 40780590
DOI: 10.1016/j.jinf.2025.106563

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