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Article

Genotypic-phenotypic discordance for cefiderocol against Enterobacter hormaechei.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Apr 2026

Dubey Vineet, Gerada Alessandro, Jones Charlotte M, Cruise James, Hope William, Howard Alex

Abstract excerpt

OBJECTIVES: The Enterobacter cloacae complex (ECC) is an emerging global cause of healthcare-associated infections, marked by high mortality and limited treatment options due to extensive antimicrobial resistance. Cefiderocol is increasingly used against carbapenem-resistant pathogens, including metallo-β-lactamase producers. However, reports of treatment failure, particularly in isolates with borderline MICs,...

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PMID: 41720210
DOI: 10.1016/j.ijid.2026.108479

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