Article

Characterization of HPV and host genome interactions in primary head and neck cancers

2020-11-08

Abstract excerpt

A significant proportion of head and neck cancer is driven by human papillomavirus (HPV) infection, and the expression of viral oncogenes is involved in the development of these tumors. However, the role of HPV integration in primary tumors beyond increasing the expression of viral oncoproteins is not understood. Here, we describe how HPV integration impacts the host genome by amplification of oncogenes and disrup...

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Literature Corpus work: 8661ed4c-59f2-52a0-84de-d4eab6d6175d
DOI: 10.17615/wkmh-9g54

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