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Genomic Landscape of Human Papillomavirus–Associated Cancers

16 Mar 2015

Abstract excerpt

Recent next-generation sequencing studies have generated a comprehensive overview of the genomic landscape of human papillomavirus (HPV)-associated cancers. This review summarizes these findings to provide insight into the tumor biology of these cancers and potential therapeutic opportunities for HPV-driven malignancies. In addition to the tumorigenic properties of the HPV oncoproteins, integration of HPV DNA...

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PMID: 25779941
DOI: 10.1158/1078-0432.ccr-14-1101

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