Article

HPV integration in head and neck cancer: downstream splicing events and expression ratios linked with poor outcomes

2025-01-20

Abstract excerpt

HPV integration (HPVint) is associated with carcinogenesis and tumor progression in HPV-associated cancers, including head and neck squamous cell carcinomas (HNSCC). While its impact on human DNA has been well characterized, its relationship with clinical outcomes remains unconfirmed. Here we investigate the consequences of HPVint both with respect to human and HPV characteristics by analyzing 261 HPV-associated H...

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Literature Corpus work: 4afbb9d1-4dfd-5f7c-a1b5-dd2328422a43
DOI: 10.1101/2025.01.17.633627

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