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Article

Characterization of HPV and host genome interactions in primary head and neck cancers

13 Oct 2014

Abstract excerpt

Previous studies have established that a subset of head and neck tumors contains human papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display distinct biological and clinical features. HPV is known to drive cancer by the actions of the E6 and E7 oncoproteins, but the molecular architecture of HPV infection and its interaction with the host genome in head and neck cancers have not been...

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PMID: 25313082
DOI: 10.1073/pnas.1416074111

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