An atlas of genetic influences on human blood metabolites.

doi:10.1038/ng.2982

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Article

An atlas of genetic influences on human blood metabolites.

Nature genetics - 1 Jun 2014

Shin So-Youn, Fauman Eric B, Petersen Ann-Kristin, Krumsiek Jan, Santos Rita, Huang Jie, Arnold Matthias, Erte Idil, Forgetta Vincenzo, Yang Tsun-Po, Walter Klaudia, Menni Cristina, Chen Lu, Vasquez Louella, Valdes Ana M, Hyde Craig L, Wang Vicky, Ziemek Daniel, Roberts Phoebe, Xi Li, Grundberg Elin, Waldenberger Melanie, Richards J Brent, Mohney Robert P, Milburn Michael V, John Sally L, Trimmer Jeff, Theis Fabian J, Overington John P, Suhre Karsten, Brosnan M Julia, Gieger Christian, Kastenmüller Gabi, Spector Tim D, Soranzo Nicole

Abstract excerpt

Genome-wide association scans with high-throughput metabolic profiling provide unprecedented insights into how genetic variation influences metabolism and complex disease. Here we report the most comprehensive exploration of genetic loci influencing human metabolism thus far, comprising 7,824 adult individuals from 2 European population studies. We report genome-wide significant associations at 145 metabolic loci...

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Identifiers

PMID: 24816252
DOI: 10.1038/ng.2982
PMCID: PMC4064254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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