Article

Genetic Architecture of Circulating Metabolic Biomarkers Across Ancestral Populations

2025-12-04

Abstract excerpt

Circulating metabolite levels hold promise for disease risk prediction, yet the genetic architecture and cross-ancestry transferability remain incompletely characterized. Here, we conducted the largest genome-wide association study in East Asians to date, quantifying 248 blood metabolic biomarkers using nuclear magnetic resonance spectroscopy in 37,969 Japanese individuals. We identified eight novel associations a...

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Literature Corpus work: 6e0344ca-0916-5420-bc8c-c7522cb58575
DOI: 10.64898/2025.12.03.25341540

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