Functional genomics of autoimmune diseases.

Abstract excerpt

For more than a decade, genome-wide association studies have been applied to autoimmune diseases and have expanded our understanding on the pathogeneses. Genetic risk factors associated with diseases and traits are essentially causative. However, elucidation of the biological mechanism of disease from genetic factors is challenging. In fact, it is difficult to identify the causal variant among multiple variants...

Topics

• Autoimmune Diseases
• Genetic Predisposition to Disease
• Genome-Wide Association Study
• Genomics
• Humans
• Polymorphism, Single Nucleotide