Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autoimmune diseases - connecting risk alleles with molecular traits of the immune system.

Nature reviews. Genetics - 1 Mar 2016

Gutierrez-Arcelus Maria, Rich Stephen S, Raychaudhuri Soumya

Abstract excerpt

Genome-wide strategies have driven the discovery of more than 300 susceptibility loci for autoimmune diseases. However, for almost all loci, understanding of the mechanisms leading to autoimmunity remains limited, and most variants that are likely to be causal are in non-coding regions of the genome. A critical next step will be to identify the in vivo and ex vivo immunophenotypes that are affected by risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Diseases
Share to Autoimmunity
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Immune System

Share to Immunophenotyping

Share to Prevalence

Source

Open in PubMed Open full text

Identifiers

PMID: 26907721
DOI: 10.1038/nrg.2015.33
PMCID: PMC4896831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autoimmune diseases - connecting risk alleles with molecular traits of the immune system.PMID 26907721Read ↗

What have we learned from six years of GWAS in autoimmune diseases, and what is next?Semantic proximity Read ↗

The immunogenetic architecture of autoimmune disease.Semantic proximity Read ↗

Innate and adaptive immune abnormalities underlying autoimmune diseases: the genetic connections.Semantic proximity Read ↗

Common genetic factors among autoimmune diseases.Semantic proximity Read ↗

The genetics of human autoimmune disease: A perspective on progress in the field and future directions.Semantic proximity Read ↗

Recent advances in the genetics of autoimmune disease.Semantic proximity Read ↗

Functional Genetics to Understand the Etiology of Autoimmunity.Semantic proximity Read ↗

Recent acquisitions on the genetic basis of autoimmune disease.Semantic proximity Read ↗

What is next after the genes for autoimmunity?Semantic proximity Read ↗

The genetic basis of autoimmunity seen through the lens of T cell functional traits.Semantic proximity Read ↗

Identifying genetic determinants of autoimmunity and immune dysregulation.Semantic proximity Read ↗

The genetics of human autoimmune disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.