Article

A systematic analysis of IBD GWAS loci identifies most probable causal genes impacting intestinal epithelial functions

2026-08-02

Abstract excerpt

<h4>Background</h4> Genome-wide association studies have identified >200 loci associated with IBD, yet the causal gene for most remains unknown. As multiple epithelial functions have been linked with susceptibility to IBD, there is a need to prioritize candidate causal genes for functional studies in this cellular context. <h4>Methods</h4> Using a standardized definition of regions implicated by index SNPs from...

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Literature Corpus work: 85849a87-6ac5-5a96-a8e5-c8602380a76c
DOI: 10.64898/2026.07.30.26359349

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