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Article

Identification of key genes as diagnostic biomarkers for IBD using bioinformatics and machine learning.

Journal of translational medicine - 3 Jul 2025

Li Tianhao, Jing Haoren, Gao Xinyu, Zhang Te, Yao Haitao, Zhang Xipeng, Zhang Mingqing

Abstract excerpt

BACKGROUND: The pathogenesis of inflammatory bowel disease (IBD) involves complex molecular mechanisms, and achieving clinical remission remains challenging. This study aims to identify IBD-potential biomarkers, analyze their correlation with immune cell infiltration, and identify genes that have a causal relationship with IBD. METHODS: RNA-seq datasets for IBD were retrieved from GEO, stratified into discovery...

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Identifiers

PMID: 40611294
DOI: 10.1186/s12967-025-06531-1
PMCID: PMC12231756

Genes

GBP5
PARP9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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