Article

Imperatorin inhibits proliferation, migration and inflammation via blocking NF-κB and MAPK pathways in rheumatoid fibroblast-like synoviocytes

2022-04-20

Abstract excerpt

<h4>Background: </h4> Rheumatoid arthritis (RA) is a chronic joint inflammatory disease that is associated with the aberrant activation of fibroblast‐like synoviocytes (FLSs). Searching for natural compounds that may suppress the activation of FLSs has become a complementary approach for RA treatment. Here, we investigated the effects and mechanisms of imperatorin (IPT) on proliferation, migration, and inflammatio...

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Literature Corpus work: 854b7874-b2ad-5fcc-b9a0-e2e978afabef
DOI: 10.21203/rs.3.rs-1560945/v1

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