Article
Identification of drug targets and potential molecular mechanisms for Wantong Jingu Tablet extract in treatment of rheumatoid arthritis: bioinformatics analysis of fibroblast-like synoviocytes
2020-05-29
Abstract excerpt
<h4>Background: </h4> Rheumatoid arthritis- fibroblast-like synoviocytes (RA-FLSs) play important roles in pathogenesis of rheumatoid arthritis (RA). Wantong Jingu Tablet (WJT), a mixture of traditional Chinese medicine, is a potentially effective therapy for RA, but its underlying mechanism is unclear. In this study, we explore the effects of WJT on human RA-FLSs and the underlying molecular mechanism. <h4>Method...
Topics
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- Cancer-related molecular mechanisms research
- Cytokine Signaling Pathways and Interactions
- Natural product bioactivities and synthesis
- Osteoarthritis Treatment and Mechanisms
- Phytochemical compounds biological activities
- Research on Leishmaniasis Studies
- Rheumatoid Arthritis Research and Therapies
- Viral Infections and Immunology Research
Identifiers and source
- Literature Corpus work
- 67b36092-4f05-5d05-9db8-eac7aa16b9b5
- DOI
- 10.21203/rs.3.rs-21336/v2
