Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes

14 Nov 2019

Abstract excerpt

Objective . Iguratimod, a novel disease-modifying anti-rheumatic drug for the treatment of rheumatoid arthritis, has been approved in China and Japan. Here, we aimed to find whether iguratimod can inhibit the aggressive behavior and promote apoptosis of rheumatoid fibroblast-like synoviocytes (RA-FLSs). Methods . The proliferation of RA-FLSs was assessed by 5-ethynyl-2 ′ -deoxyuridine test and Cell Counting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders Research
Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Rheumatoid Arthritis Research and Therapies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31828173
DOI: 10.1155/2019/6929286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like SynoviocytesPMID 31828173Read ↗

Imperatorin inhibits proliferation, migration and inflammation via blocking NF-κB and MAPK pathways in rheumatoid fibroblast-like synoviocytesSemantic proximity Read ↗

Identification of drug targets and potential molecular mechanisms for Wantong Jingu Tablet extract in treatment of rheumatoid arthritis: bioinformatics analysis of fibroblast-like synoviocytesSemantic proximity Read ↗

Transformation of fibroblast‐like synoviocytes in rheumatoid arthritis; from a friend to foeSemantic proximity Read ↗

Expression of AIM2 in Rheumatoid Arthritis and Its Role on Fibroblast-Like SynoviocytesSemantic proximity Read ↗

Wutou decoction ameliorates rheumatoid arthritis through inhibiting hypoxia-induced invasive phenotype of fibroblast-like synoviocytes mediated by the Notch pathway.Semantic proximity Read ↗

miR-410-3p regulates proliferation and apoptosis of fibroblast-like synoviocytes by targeting YY1 in rheumatoid arthritisSemantic proximity Read ↗

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis.Semantic proximity Read ↗

Role of Fibroblast Activation Protein Alpha in Fibroblast-like Synoviocytes of Rheumatoid ArthritisSemantic proximity Read ↗

Influence of resveratrol on rheumatoid fibroblast-like synoviocytes analysed with gene chip transcription.Semantic proximity Read ↗

IGF2BP2 regulates the inflammation of fibroblast-like synoviocytes via GSTM5 in rheumatoid arthritisSemantic proximity Read ↗

Identification of key regulators for the migration and invasion of rheumatoid synoviocytes through a systems approachSemantic proximity Read ↗

Stable activation of fibroblasts in rheumatic arthritis-causes and consequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.