Article

The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis

2020-04-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Reactive oxygen species (ROS) regulate the migration and invasion of fibroblast-like synoviocytes (FLS), which are key effector cells in rheumatoid arthritis (RA) pathogenesis. Nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) induces ROS generation and consequently, enhances cell migration. Despite the important interrelationship between RA, FLS, and...

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Literature Corpus work: 10b689aa-d271-595f-97a6-40848ed8636e
DOI: 10.21203/rs.2.20756/v3

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