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Article

Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis.

Scientific reports - 12 Nov 2021

Køster Ditte, Egedal Johanne Hovgaard, Lomholt Søren, Hvid Malene, Jakobsen Martin R, Müller-Ladner Ulf, Eibel Hermann, Deleuran Bent, Kragstrup Tue Wenzel, Neumann Elena, Nielsen Morten Aagaard

Abstract excerpt

Fibroblast-like synoviocytes (FLS) play an important pathological role in persistent inflammatory joint diseases such as rheumatoid arthritis (RA). These cells have primarily been characterized in the RA synovial membrane. Here we aim to phenotypically and functionally characterize cultured synovial fluid-derived FLS (sfRA-FLS). Paired peripheral blood mononuclear cells (PBMC) and sfRA-FLS from patients with RA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34772990
DOI: 10.1038/s41598-021-01692-7
PMCID: PMC8590001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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